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RESEARCH PRODUCT

Biological effects of high molecular weight lignin derivatives

Piia PessalaTarja NakariJaakko PaasivirtaSirpa HerveJuha KnuutinenJukka KukkolaEija Schultz

subject

Paperendocrine systemHealth Toxicology and MutagenesisDaphnia magnaLigninWaste Disposal Fluidcomplex mixturesMicrobiologyElectron Transportchemistry.chemical_compoundToxicity TestsCytochrome P-450 CYP1A1AnimalsLigninBioassayFinlandVibriobiologyfungitechnology industry and agriculturePublic Health Environmental and Occupational Healthfood and beveragesBiological activityGeneral Medicinebiology.organism_classificationPollutionIn vitroVibrioReverse electron flowDaphniachemistryBiochemistryOncorhynchus mykissHepatocytesBiological AssayWater Pollutants ChemicalBacteria

description

Abstract A number of high molecular weight (HMW) lignin derivatives possessing varied chemical properties were screened for their biological effects in order to obtain more information on the possible structural features of HMW lignin-related effects. The studied compounds were both commercial and in-house extracted lignin derivatives. Bioassays used include reverse electron transport (RET), Vibrio fischeri, Daphnia magna , and juvenile rainbow trout ( Oncorhynchus mykiss) hepatocytes. The studied lignin derivatives inhibited the in vitro systems and luminescence of V. fischeri bacteria to some extent–daphnids were not affected. It seems that, at least in the RET assay, certain pH-dependent functional groups in lignin may be of importance regarding the biological effects.

yearjournalcountryeditionlanguage
2010-10-01Ecotoxicology and Environmental Safety
https://doi.org/10.1016/j.ecoenv.2010.02.004