6533b82afe1ef96bd128c078

RESEARCH PRODUCT

Effect of Intra-Arterial Infusion of Papaverine Hydrochloride on Brain Tissue Oxygen Pressure in the Management of Severe Vasospasm Following Aneurysmal Subarachnoid Hemorrhage

Kurt RingelAxel PerneczkyPeter StoeterD. MauerRonald FilippiRobert ReischH. Böcher-schwarz

subject

Subarachnoid hemorrhagePapaverine Hydrochloridebusiness.industryVasospasmIntra arterial infusionPerioperativemedicine.diseaseIntensive care unitlaw.inventionCerebral vasospasmCerebral blood flowlawAnesthesiamedicinecardiovascular diseasesbusiness

description

Despite considerable advances in diagnostic, surgical and interventional techniques, the overall outcome for patients with aneurysmal subarachnoid hemorrhage remains poor. Concerning perioperative course, cerebral ischaemia is one of the major factors causing secondary brain demage. The aim of all therapeutic interventions is the stabilization and maintance of cerebral blood flow and tissue oxygenation in order to prevent cerebral ischaemia and consecutively brain infarction [1].

https://doi.org/10.1007/978-3-7091-6232-3_40