6533b82afe1ef96bd128ca39

RESEARCH PRODUCT

Über die Hemmung von Desoxyribonucleotide spaltenden Fermenten durch Colchicin

G. SiebertK. LangH. Oswald

subject

Pharmacologychemistry.chemical_classificationDeaminationCell BiologyBiologyDephosphorylationCellular and Molecular Neurosciencechemistry.chemical_compoundEnzymechemistryBiochemistryMolecular MedicineColchicineNucleotideMolecular BiologyMitosis

description

The authors raise the question, if enzymatic processes possibly linked with the mitotic cell division may be influenced by mitotic poisons. The presented date show an inhibition of the dephosphorylation of desoxyribonucleotides at a rate of about 50% and of the deamination of about 40% by colchicine (final concentration 1·2·10−2M).

https://doi.org/10.1007/bf02165260