6533b82afe1ef96bd128ccbf

RESEARCH PRODUCT

AnABlast: Re-searching for Protein-Coding Sequences in Genomic Regions

Alejandro RubioJuan JimenezAndrés GarzónPablo MierAntonio J. Pérez-pulidoMiguel A. Andrade-navarroCarlos S. Casimiro-soriguer

subject

Fossil DNA sequencesProtein coding0303 health sciencesGene predictionCoding DNA sequences030302 biochemistry & molecular biologyComputational biologyBiologyGene findingDNA sequencing03 medical and health sciencesExonchemistry.chemical_compoundIntergenic regionchemistryHomologous chromosomeSmall genesGeneIn silico annotation toolDNA030304 developmental biology

description

AnABlast is a computational tool that highlights protein-coding regions within intergenic and intronic DNA sequences which escape detection by standard gene prediction algorithms. DNA sequences with small protein-coding genes or exons, complex intron-containing genes, or degenerated DNA fragments are efficiently targeted by AnABlast. Furthermore, this algorithm is particularly useful in detecting protein-coding sequences with nonsignificant homologs to sequences in databases. AnABlast can be executed online at http://www.bioinfocabd.upo.es/anablast/ .

https://doi.org/10.1007/978-1-4939-9173-0_12