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RESEARCH PRODUCT

Epidemiologic analysis of salivary gland tumors over a 10-years period diagnosed in a northeast Brazilian population

Sílvia Ferreira De SousaRicardo-luiz-cavalcanti Albuquerque-júniorAna Carolina Penha CoimbraJoão Vitor Rocha SilvaClauberto Rodrigues De OliveiraIlmara Silva Do NascimentoMaria Eliane De AndradeCiro Dantas SoaresJohn Lennon Silva CunhaOslei Paes De Almeida

subject

Malemedicine.medical_specialtyAdenomaAdenoma PleomorphicPleomorphic adenoma03 medical and health sciences0302 clinical medicineMucoepidermoid carcinomaMajor Salivary GlandEpidemiologymedicineHumansGeneral DentistryRetrospective StudiesOral Medicine and PathologySalivary glandbusiness.industryResearchRetrospective cohort study030206 dentistrySalivary Gland Neoplasmsmedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologyParotid glandCross-Sectional Studiesmedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASFemaleSurgerybusinessBrazil

description

Background Salivary gland tumors (SGT) correspond to a heterogeneous group of lesions with variable biological behavior. The present study aimed to determine the distribution and demographic findings of salivary gland neoplasms in a northeast Brazilian population. Material and Methods A retrospective descriptive cross-sectional study was performed. A total of 588 cases of SGT were diagnosed between 2006 and 2016 of 4 pathology services in the state of Sergipe, Brazil. All cases were reviewed, and data such as sex, age, anatomical location, and histopathological diagnosis were collected. Results A total of 470 (79.9%) tumors were benign and 118 (20.1%) were malignant. The majority of the patients were females (n=328, 55.8%) with an overall female:male ratio of 1.2:1. The major salivary glands were affected more than the minor glands (69.5% vs. 30.5%). Pleomorphic adenoma (n=419, 71.3%) and mucoepidermoid carcinoma (n=29, 4.9%) were the most frequent benign and malignant tumors, respectively. In addition, both benign and malignant tumors occurred more frequently in the parotid gland (n=300, 51%, p<0.05). Conclusions The epidemiologic profile and clinical characteristics of SGT were similar to those described in other countries and other regions of Brazil. Epidemiological studies of SGT help to understand their clinical and pathological features and are essential to establish the proper management and prognosis. Key words:Salivary gland, tumors, epidemiology, head and neck pathology.

https://hdl.handle.net/10550/77147