6533b82bfe1ef96bd128d506

RESEARCH PRODUCT

Metabolism of stilbene phytoalexins by Botrytis cinerea: 1. Characterization of a resveratrol dehydrodimer

Anne-céline BreuilPhilippe MeunierNadine PirioPhilippe JeandetMarielle AdrianRoger Bessis

subject

chemistry.chemical_classificationbiologyStereochemistryMetabolitePhytoalexinOrganic ChemistryMetabolismResveratrolbiology.organism_classificationBiochemistrychemistry.chemical_compoundEnzymeBiochemistrychemistryDrug DiscoveryDegradation processCausal organismBotrytis cinerea

description

Abstract Resveratrol, a grapevine phytoalexin, is metabolized by a laccase-like stilbene-oxidase of Botrytis cinerea, the causal organism for grey mould. Characterization of one major metabolite formed during this degradation process as a resveratrol dehydrodimer allowed us to precize the reaction mechanism of this enzyme on stilbenes.

https://doi.org/10.1016/s0040-4039(97)10622-0