Mechanismus und Reaktionswege der Xanthenylierung an ambidenten nukleophilen Arzneistoffen

6533b82bfe1ef96bd128d50f

RESEARCH PRODUCT

Mechanismus und Reaktionswege der Xanthenylierung an ambidenten nukleophilen Arzneistoffen

subject

chemistry.chemical_classification chemistry.chemical_compound SN1 reaction Nucleophile Bicyclic molecule chemistry Stereochemistry Drug Discovery Pharmaceutical Science Reaction path Xanthydrol Sulfonamide

description

Am Beispiel der ambidenten nukleophilen Arzneistoffe 4-Aminobenzolsulfonamid (3), Indometacin (7) und Phenylbutazon (10) werden Aralkylierungen mit dem SN1-aktiven Reagens Xanthydrol (1) vorgestellt. Mechanism and Reaction Path of the Xanthenylation of Ambident Nucleophilic Drugs The aralkylation of ambident nucleophilic drugs, e.g. 4-aminobenzenesulfonamide (3), indometacine (7) and phenylbutazone (10), with SN1-active xanthydrol (1) is described.

year	journal	country	edition	language
1986-01-01	Archiv der Pharmazie

https://doi.org/10.1002/ardp.19863190814

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