Search results for "Xanthydrol"
showing 4 items of 4 documents
Determination of N-acetyl-l-glutamine in urine by HPLC
1986
The determination of N-acetyl-l-glutamine (AC-GLN) in urine of rats after derivatization with xanthydrol by HPLC is described. The urine samples were collected from two groups of rats, one group fed normal nutrition, the other treated with AC-GLN. About 5 mM/l AC-GLN was detected in urine of untreated animals, whereas the excretion of the other group was in the range of 50 mM/l corresponding to about 50 wt.-% of the given AC-GLN.
Regioselective proton-catalyzed diarylmethylation of indoles with 9H-xanthydrol, dibenzosuberenol, and bis[4-dimethylaminophenyl]methanol
1988
3-Isopropylindole (4) is xanthenylated both at N-1 (stereocontrolled major reaction), C-2, and on the phenyl nucleus of the indole skeleton by xanthydrol (1). Other carbinols such as dibenzosuberenol (2) and bis[4-dimethylaminophenyl]methanol (3) with lower electrophilic SN1 activities than 1 do not react with 4 but do react very selectively with simple methylindoles to form diarylmethylated derivatives.
Mechanismus und Reaktionswege der Xanthenylierung an ambidenten nukleophilen Arzneistoffen
1986
Am Beispiel der ambidenten nukleophilen Arzneistoffe 4-Aminobenzolsulfonamid (3), Indometacin (7) und Phenylbutazon (10) werden Aralkylierungen mit dem SN1-aktiven Reagens Xanthydrol (1) vorgestellt. Mechanism and Reaction Path of the Xanthenylation of Ambident Nucleophilic Drugs The aralkylation of ambident nucleophilic drugs, e.g. 4-aminobenzenesulfonamide (3), indometacine (7) and phenylbutazone (10), with SN1-active xanthydrol (1) is described.
ChemInform Abstract: Regioselective Proton-Catalyzed Diarylmethylation of Indoles with 9H-Xanthydrol, Dibenzosuberenol, and Bis(4-dimethylaminophenyl…
1989
3-Isopropylindole (4) is xanthenylated both at N-1 (stereocontrolled major reaction), C-2, and on the phenyl nucleus of the indole skeleton by xanthydrol (1). Other carbinols such as dibenzosuberenol (2) and bis[4-dimethylaminophenyl]methanol (3) with lower electrophilic SN1 activities than 1 do not react with 4 but do react very selectively with simple methylindoles to form diarylmethylated derivatives.