6533b822fe1ef96bd127caad
RESEARCH PRODUCT
Determination of N-acetyl-l-glutamine in urine by HPLC
Ingo LüderwaldUtha HellmannMonika Neuhäusersubject
Excretionchemistry.chemical_compoundChromatographyChemistryClinical BiochemistryN-acetyl-L-glutamineGeneral Materials ScienceGeneral MedicineUrineXanthydrolDerivatizationHigh-performance liquid chromatographyAnalytical Chemistrydescription
The determination of N-acetyl-l-glutamine (AC-GLN) in urine of rats after derivatization with xanthydrol by HPLC is described. The urine samples were collected from two groups of rats, one group fed normal nutrition, the other treated with AC-GLN. About 5 mM/l AC-GLN was detected in urine of untreated animals, whereas the excretion of the other group was in the range of 50 mM/l corresponding to about 50 wt.-% of the given AC-GLN.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1986-01-01 | Fresenius' Zeitschrift für analytische Chemie |