6533b82cfe1ef96bd128f373
RESEARCH PRODUCT
La réponse immunitaire anti-tumorale dans le cancer du sein : état des lieux et perspectives thérapeutiques
Laurent ArnouldMarion ThibaudinIsabelle DesmoulinsBruno CoudertMarie ChaixVeronique LorgisFrançois GhiringhelliPierre FumoleauValentin DerangèreSylvain Ladoiresubject
0301 basic medicineOncologymedicine.medical_specialtybusiness.industrymedicine.medical_treatmentImmunotherapymedicine.disease3. Good healthPathology and Forensic MedicineBlockadeImmunosurveillanceVaccination03 medical and health sciences030104 developmental biology0302 clinical medicineBreast cancerImmune systemTumor Escape030220 oncology & carcinogenesisInternal medicinemedicineBreast carcinomabusinessdescription
The role of the immune response in breast cancer is now well recognized and increasingly taken in account. The goal of this article is, in the first part, to underline its prognostic impact and to precise the immunosurvelliance, immunoselection and the immunosubversion concepts involved in the control and evasion of breast carcinoma. In the second part, therapeutic strategies for the restauration of anti-tumor immunity are developed. Vaccination strategies and checkpoints inhibitors blockade strategies are discussed as well as the immunogenic death linked to the conventional treatments of breast cancer.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-02-01 | Annales de Pathologie |