6533b82cfe1ef96bd128f687

RESEARCH PRODUCT

Characterization of the carbapenem-hydrolyzing oxacillinase OXA-58 in an Acinetobacter phenon 6/ct13TU clinical isolate

Javier Sánchez-céspedesJordi VilaVerónica AlbaPaula EspinalM. Dolores BlascoSara MartíMarc Ruiz

subject

DNA BacterialMicrobiology (medical)CarbapenemGene Transfer HorizontalSequence HomologyBiologybeta-LactamasesHomology (biology)MicrobiologyAntibiotic resistancePlasmidmedicineHumansElectrophoresis Agar GelAcinetobacterNucleic Acid HybridizationSequence Analysis DNAGeneral Medicinebiochemical phenomena metabolism and nutritionAcinetobacterbacterial infections and mycosesbiology.organism_classificationAcinetobacter baumanniiInfectious DiseasesCarbapenemsGenes BacterialNeisseriaceaeBacteriaAcinetobacter InfectionsPlasmidsmedicine.drug

description

The bla(OXA-58) gene identified in the Acinetobacter phenon 6/ct13TU clinical isolate presented 100% homology with the same gene in Acinetobacter baumannii. Its location in a plasmid suggests that these resistance genes may be transferred from 1 species to another.

https://doi.org/10.1016/j.diagmicrobio.2008.03.014