0000000000172656

AUTHOR

Paula Espinal

0000-0002-1014-8936

showing 2 related works from this author

Characterization of the Carbapenem-Hydrolyzing Oxacillinase Oxa-58 in an Acinetobacter Genospecies 3 Clinical Isolate

2008

ABSTRACT Based on imipenem resistance in an Acinetobacter genospecies 3 clinical isolate, we were able to identify, for the first time in this genomic species, a plasmid-encoded bla OXA-58 gene that was 100% homologous to the same gene in Acinetobacter baumannii .

ImipenemCarbapenemMolecular Sequence DataMicrobial Sensitivity TestsBiologybeta-LactamasesMicrobiologyPlasmidBacterial ProteinsMechanisms of Resistancepolycyclic compoundsmedicineHumansPharmacology (medical)Antibacterial agentPharmacologyAcinetobacterBase SequenceSequence Analysis DNAbiochemical phenomena metabolism and nutritionAcinetobacterbacterial infections and mycosesbiology.organism_classificationAnti-Bacterial AgentsAcinetobacter baumanniiImipenemInfectious DiseasesCarbapenemsNeisseriaceaeBacteriaAcinetobacter InfectionsPlasmidsmedicine.drugAntimicrobial Agents and Chemotherapy
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Characterization of the carbapenem-hydrolyzing oxacillinase OXA-58 in an Acinetobacter phenon 6/ct13TU clinical isolate

2008

The bla(OXA-58) gene identified in the Acinetobacter phenon 6/ct13TU clinical isolate presented 100% homology with the same gene in Acinetobacter baumannii. Its location in a plasmid suggests that these resistance genes may be transferred from 1 species to another.

DNA BacterialMicrobiology (medical)CarbapenemGene Transfer HorizontalSequence HomologyBiologybeta-LactamasesHomology (biology)MicrobiologyAntibiotic resistancePlasmidmedicineHumansElectrophoresis Agar GelAcinetobacterNucleic Acid HybridizationSequence Analysis DNAGeneral Medicinebiochemical phenomena metabolism and nutritionAcinetobacterbacterial infections and mycosesbiology.organism_classificationAcinetobacter baumanniiInfectious DiseasesCarbapenemsGenes BacterialNeisseriaceaeBacteriaAcinetobacter InfectionsPlasmidsmedicine.drugDiagnostic Microbiology and Infectious Disease
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