Characterization of the Carbapenem-Hydrolyzing Oxacillinase Oxa-58 in an Acinetobacter Genospecies 3 Clinical Isolate

6533b7d2fe1ef96bd125e109

RESEARCH PRODUCT

Characterization of the Carbapenem-Hydrolyzing Oxacillinase Oxa-58 in an Acinetobacter Genospecies 3 Clinical Isolate

Javier Sánchez-céspedes Paula Espinal Jordi Vila M. Dolores Blasco Sara Martí Verónica Alba Felipe Fernández-cuenca Marc Ruiz ÁLvaro Pascual

subject

Imipenem Carbapenem Molecular Sequence Data Microbial Sensitivity Tests Biology beta-Lactamases Microbiology Plasmid Bacterial Proteins Mechanisms of Resistance polycyclic compounds medicine Humans Pharmacology (medical)Antibacterial agent Pharmacology Acinetobacter Base Sequence Sequence Analysis DNA biochemical phenomena metabolism and nutrition Acinetobacter bacterial infections and mycoses biology.organism_classification Anti-Bacterial Agents Acinetobacter baumannii Imipenem Infectious Diseases Carbapenems Neisseriaceae Bacteria Acinetobacter Infections Plasmids medicine.drug

description

ABSTRACT Based on imipenem resistance in an Acinetobacter genospecies 3 clinical isolate, we were able to identify, for the first time in this genomic species, a plasmid-encoded bla OXA-58 gene that was 100% homologous to the same gene in Acinetobacter baumannii .

year	journal	country	edition	language
2008-08-01	Antimicrobial Agents and Chemotherapy

https://doi.org/10.1128/aac.00072-08

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