6533b82cfe1ef96bd128f735

RESEARCH PRODUCT

Liver transplantation for hepatocellular carcinoma with intrahepatic lymphatic invasion: case reports.

Arnold RadtkeIoannis FouzasErnesto P. MolmentiGeorge SgourakisHauke LangM. MalagóGeorgios C. Sotiropoulos

subject

MalePathologymedicine.medical_specialtyCarcinoma HepatocellularLymphovascular invasionmedicine.medical_treatmentLiver transplantationGastroenterologyMetastasisInternal medicinemedicineHumansNeoplasm InvasivenessLymph nodeTransplantationbusiness.industryLiver NeoplasmsCancerMiddle Agedmedicine.diseasedigestive system diseasesLiver Transplantationsurgical procedures operativeLymphatic systemmedicine.anatomical_structureTreatment OutcomeHepatocellular carcinomaSurgeryFemaleLiver cancerbusiness

description

Multiple studies addressing liver transplantation (OLT) for hepatocellular carcinoma (HCC) have identified various prognostic determinants of tumor recurrence and decreased patient survival. However, little information is available on the impact of intrahepatic lymphatic invasion on tumor recurrence and survival after OLT for HCC. Intrahepatic lymphatic invasion was observed in 1.4% (n = 2) of liver explants with HCC in our series. Both recipients are alive without tumor recurrence at 16 and 39 months post-OLT, respectively. Intrahepatic lymphatic invasion may not be an absolute adverse prognostic factor in cases of HCC with no hilar lymph node involvement at the time of OLT.

yearjournalcountryeditionlanguage
2008-11-01Transplantation proceedings
10.1016/j.transproceed.2008.08.071https://pubmed.ncbi.nlm.nih.gov/19010238