6533b82cfe1ef96bd128f743
RESEARCH PRODUCT
Computational fluid dynamics of the ascending aorta before the onset of type A aortic dissection.
Salvatore PastaPietro Giorgio MalvindiGiuseppe Maria RaffaSteven Liveseysubject
Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialty0206 medical engineeringBlood Pressure02 engineering and technologyDissection (medical)030204 cardiovascular system & hematologyAortographyComputer03 medical and health sciencesAortic aneurysm0302 clinical medicineAneurysmAneurysm Dissectingmedicine.arteryInternal medicineAscending aortamedicineHumansComputer SimulationAortaAortic dissectionAortabusiness.industryModels CardiovascularSettore ING-IND/34 - Bioingegneria IndustrialeHydrodynamicGeneral Medicinemedicine.disease020601 biomedical engineeringUnicuspid aortic valveAortic wallAortic AneurysmAortic Dissectioncardiovascular systemCardiologyHydrodynamicsSurgeryStress MechanicalCardiology and Cardiovascular MedicinebusinessTomography X-Ray ComputedBlood Flow VelocityHumandescription
We performed a pre-dissection computational fluid analysis of an ascending aortic aneurysm associated with unicuspid aortic valve. The analysis showed an abnormal helical flow pattern inside the aneurysm and an increased wall stress on the right postero-lateral wall of the ascending aorta. These values were largely higher than the theoretical cut-off for aortic wall dissection, their topographic distribution followed the intimal tear site as subsequently diagnosed by computed tomography scan and confirmed during the operation for dissection repair.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-06-06 | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery |