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RESEARCH PRODUCT
Dual Diagnostic Role of 123I-MIBG Scintigraphy in Inverted-Takotsubo Pattern Cardiomyopathy
Yves CottinOlivier HumbertCarole RichardAlexandre CochetAurélie GudjoncikSalim KanounKarim Stamboulsubject
AdultMalemedicine.medical_specialtyCardiomyopathy123i mibg scintigraphyAdrenergic[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine030204 cardiovascular system & hematologyScintigraphy3-Iodobenzylguanidine030218 nuclear medicine & medical imaging[ SDV.IB.MN ] Life Sciences [q-bio]/Bioengineering/Nuclear medicinePheochromocytoma03 medical and health sciencesBasal (phylogenetics)0302 clinical medicineTakotsubo CardiomyopathyInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingComputingMilieux_MISCELLANEOUSmedicine.diagnostic_testbusiness.industryGeneral Medicinemedicine.disease3. Good health3-IodobenzylguanidinePositron emission tomographyPositron-Emission TomographyCardiologyRadiopharmaceuticalsbusinessdescription
We highlight the dual role of I-MIBG scintigraphy in inverted-Takotsubo pattern cardiomyopathy, the diagnosis of which is sometimes challenging: Firstly, I-MIBG scintigraphy can show myocardial sympathetic dysfunction (low I-MIBG uptake) in the hypokinetic basal segments, sparing the left ventricle apex. It is helpful in the imaging diagnosis of inverted-Takotsubo pattern cardiomyopathy and confirms that acute dysfunction of myocardial sympathetic nerve endings occurs with this cardiomyopathy. Secondly, I-MIBG scintigraphy is an accurate imaging examination to detect and localize pheochromocytoma; it can help in the search for an endogenous cause of this adrenergic stress-related cardiomyopathy.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-01-01 |