Drug Synergism: Studies of Combination of RK-52 and Curcumin against Rhodesain of Trypanosoma brucei rhodesiense

6533b82dfe1ef96bd1291230

RESEARCH PRODUCT

Drug Synergism: Studies of Combination of RK-52 and Curcumin against Rhodesain of Trypanosoma brucei rhodesiense

Carla Di Chio Tanja Schirmeister Roberta Ettari Maria Zappalà Alessandro Allegra Santo Previti Santina Maiorana

subject

biology 010405 organic chemistry Organic Chemistry Trypanosoma brucei rhodesiense biology.organism_classification medicine.disease 01 natural sciences Biochemistry Virology Drug synergism 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry.chemical_compound chemistry parasitic diseases Drug Discovery Trypanosoma medicine Curcumin Parasite hosting African trypanosomiasis

description

Rhodesain is an enzyme essential for the life of Trypanosoma brucei rhodesiense, a parasite causing a rapid-onset form of Human African Trypanosomiasis. RK-52 is a synthetic inhibitor of rhodesain,...

year	journal	country	edition	language
2020-01-15	ACS Medicinal Chemistry Letters

https://doi.org/10.1021/acsmedchemlett.9b00635

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