6533b82dfe1ef96bd1291405

RESEARCH PRODUCT

Histo-blood group antigens in children with symptomatic rotavirus infection

Noelia Carmona-vicenteJavier BuesaRaúl Pérez-ortínSusana Vila-vicentCristina Santiso-bellónJesús Rodríguez-díaz

subject

0301 basic medicineMaleSalivaviruseslcsh:QR1-502medicine.disease_causelcsh:MicrobiologysusceptibilityBlood group antigensFecesfluids and secretionsRotavirusGenotypeChildGastroenterologiaeducation.field_of_studyvirus diseaseshisto-blood group antigens (HBGAs)Rotavirus infectionInfectious DiseasesChild PreschoolBlood Group AntigensFemalegastroenteritisGenotypeVirus RNA030106 microbiologyPopulationRotavirus InfectionsArticlesecretor03 medical and health sciencesAntigenVirologyABO blood group systemmedicineHumansGenetic Predisposition to DiseaseABO group antigenseducationSalivabusiness.industryInfant NewbornInfantVirology030104 developmental biologyrotavirusLewisSpainbusiness

description

Group A rotaviruses are a major cause of acute gastroenteritis in children. The diversity and unequal geographical prevalence of rotavirus genotypes have been linked to histo-blood group antigens (HBGAs) in different human populations. In order to evaluate the role of HBGAs in rotavirus infections in our population, secretor status (FUT2+), ABO blood group, and Lewis antigens were determined in children attended for rotavirus gastroenteritis in Valencia, Spain. During three consecutive years (2013&ndash

10.3390/v11040339https://doi.org/10.3390/v11040339