6533b82dfe1ef96bd1292007

RESEARCH PRODUCT

Sudden death due to cardiac sarcoidosis in a case of suspected homicide

G. FechnerBernd BrinkmannS. Ogbuihi

subject

AdultMalemedicine.medical_specialtyPathologySarcoidosisAutopsySudden deathPathology and Forensic MedicineDiagnosis DifferentialHomicideFibrosishemic and lymphatic diseasesInternal medicineHumansMedicineInterventricular septumbusiness.industryMyocardiummedicine.diseaseDeath Sudden Cardiacmedicine.anatomical_structureVentricleConcomitantCardiologyLymphCardiomyopathiesHomicidebusinessEndocardium

description

In a case of suspected homicide death due to natural causes — cardiac death (SCD) — was found at autopsy. Despite an extensive replacement of myocardial tissue by sarcoid granulomata there was no history of cardiac dysfunction or preceding symptoms. The transmurally infiltrating granulomata and the concomitant fibrosis were predominantly confluent. They occupied vast areas within the interventricular septum and the adjacent posterior wall of the left ventricle. The only other organs involved were mediastinal lymph nodes, which appeared macroscopically normal.

https://doi.org/10.1007/bf01225048