6533b82efe1ef96bd129298c
RESEARCH PRODUCT
Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era
Salvatore De RosaCarmen SpaccarotellaCristina BassoMaria Pia CalabròAntonio CurcioPasquale Perrone FilardiMassimo ManconeGiuseppe MercuroSaverio MuscoliSavina NodariRoberto PedrinelliGianfranco SinagraCiro IndolfiFilippo AngeliniFrancesco BarillàAntonio BartorelliFrancesco BenedettoPaola BernabòLeonardo BologneseMartina BrianiLuisa CacciavillaniAlice CalabresePaolo CalabròLuigi CaliendoLeonardo CalòGianni CasellaGavino CasuClaudio CavalliniQuirino CiampiMarco CicconeMichele ComitoElena CorradaFilippo CreaAntonello D’andreaMaurizio D’urbanoRaffaele De CaterinaGaetano De FerrariRoberto De PontiAlessio Della MattiaCarlo Di MarioDonazzan LGiovanni EspositoFrancesco FedeleAlessandro FerraroGennaro GalassoNazzareno GalièMassimiliano GnecchiPaolo GolinoBruno GoliaPasquale GuariniCiro IndolfiSergio LeonardiNicola LocuratoloFrancesco LuzzaVincenzo ManganielloMaria Francesca MarchettiGiancarlo MarenziAlberto MargonatoLuigi MeloniMarco MetraMarco MiloAnnalisa MongiardoLuca MonzoCarmine MoriscoSavina NodariGiuseppina NovoStefano PancaldiMatteo ParolloGiovanni PaternòGiuseppe PattiSilvia PrioriAmelia RaveraAntonio Giuseppe RebuzziMassimo RossiMarino ScherilloFranco SempriniMichele SenniGerolamo SibilioGianfranco SinagraMassimo SivigliaCorrado TamburinoGianfranco TortoriciFrancesco VersaceBruno VillariMassimo Volpesubject
MaleMyocardial Infarction030204 cardiovascular system & hematologySettore MED/110302 clinical medicineAcute myocardial infarction Cardiac care units STEMI Aged Aged 80 and over COVID-19 Female Hospitalization Humans Italy Male Middle Aged SARS-CoV-2 Betacoronavirus Coronavirus Infections Myocardial Infarction Pandemics Pneumonia ViralCase fatality rate80 and overMedicine030212 general & internal medicineMyocardial infarctionViralAged 80 and overAcute myocardial infarction; Cardiac care units; COVID-19; SARS-CoV2; STEMI; Aged; Aged 80 and over; Female; Hospitalization; Humans; Italy; Male; Middle Aged; Betacoronavirus; Coronavirus Infections; Myocardial Infarction; Pandemics; Pneumonia ViralMiddle AgedHospitalizationItalyFemaleCardiology and Cardiovascular MedicineCoronavirus InfectionsHumanmedicine.medical_specialtyPneumonia ViralFast Track Clinical ResearchCardiac care unitsAcute myocardial infarctionSTEMI03 medical and health sciencesBetacoronavirusCardiac care unitHumansAcute myocardial infarction; COVID-19; Cardiac care units; SARS-CoV2; STEMIcardiovascular diseasesPandemicsAgedBetacoronaviruPandemicbusiness.industryCoronavirus InfectionSARS-CoV-2COVID-19Pneumoniamedicine.diseaseacute myocardial infarction; cardiac care units; COVID-19; SARS-CoV2; STEMIConfidence intervalRelative riskEmergency medicineSettore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARESARS-CoV2Myocardial infarction complicationsObservational studyMyocardial infarction diagnosisbusinessComplicationdescription
Abstract Aims To evaluate the impact of the COVID-19 pandemic on patient admissions to Italian cardiac care units (CCUs). Methods and Results We conducted a multicentre, observational, nationwide survey to collect data on admissions for acute myocardial infarction (AMI) at Italian CCUs throughout a 1 week period during the COVID-19 outbreak, compared with the equivalent week in 2019. We observed a 48.4% reduction in admissions for AMI compared with the equivalent week in 2019 (P < 0.001). The reduction was significant for both ST-segment elevation myocardial infarction [STEMI; 26.5%, 95% confidence interval (CI) 21.7–32.3; P = 0.009] and non-STEMI (NSTEMI; 65.1%, 95% CI 60.3–70.3; P < 0.001). Among STEMIs, the reduction was higher for women (41.2%; P = 0.011) than men (17.8%; P = 0.191). A similar reduction in AMI admissions was registered in North Italy (52.1%), Central Italy (59.3%), and South Italy (52.1%). The STEMI case fatality rate during the pandemic was substantially increased compared with 2019 [risk ratio (RR) = 3.3, 95% CI 1.7–6.6; P < 0.001]. A parallel increase in complications was also registered (RR = 1.8, 95% CI 1.1–2.8; P = 0.009). Conclusion Admissions for AMI were significantly reduced during the COVID-19 pandemic across Italy, with a parallel increase in fatality and complication rates. This constitutes a serious social issue, demanding attention by the scientific and healthcare communities and public regulatory agencies.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-05-15 |