6533b82efe1ef96bd1292a58
RESEARCH PRODUCT
3'-Arylazido-beta-alanyl-2-azido ATP, a cross-linking photoaffinity label for F1ATPases.
Hans-jochen SchäferGabriele RathgeberSauer HeKlaus DoseTrommer Wesubject
chemistry.chemical_classificationAzidesPhotoaffinity labelingbiologyLightStereochemistryAffinity Labelsbiology.organism_classificationGeneral Biochemistry Genetics and Molecular BiologyMicrococcuschemistry.chemical_compoundKineticsProton-Translocating ATPasesEnzymeAdenosine TriphosphatechemistryIndicators and ReagentsBifunctionalBeta (finance)Micrococcus luteusDerivative (chemistry)description
Abstract The synthesis of the 3′-arylazido-2-azido ATP derivative 3′-O-{3-[N-(4-azido-2-nitrophenyl)-amino]propionyl}2-azido-adenosine 5′-triphosphate (2,3′-DiN3ATP) is described. The bifunc tional photoreactive ATP analog is characterized spectroscopically. Photoaffinity labeling of F, ATPase from Micrococcus luteus by this analog results in the inactivation of the enzyme and in the formation of higher molecular weight cross-links,
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1989-11-01 | Zeitschrift fur Naturforschung. C, Journal of biosciences |