6533b82efe1ef96bd12932be

RESEARCH PRODUCT

Data on the effects of low iron diet on serum lipid profile in HCV transgenic mouse model

Carmine ManconeRosario AmatoAlice ConigliaroViviana Costa

subject

0301 basic medicineGenetically modified mousemedicine.medical_specialtyLow density lipoproteins3304High densityLow density lipoproteinlcsh:Computer applications to medicine. Medical informaticsTriglyceride03 medical and health sciences0302 clinical medicineInternal medicinemedicineIron depletion; Low density lipoproteins; Triglycerides; 3304; MultidisciplinarySerum triglycerideslcsh:Science (General)TriglyceridesData ArticleDietary ironMultidisciplinarymedicine.diagnostic_testChemistrymedicine.diseaseIron depletion030104 developmental biologyEndocrinologyBiochemistrySerum ironlcsh:R858-859.7030211 gastroenterology & hepatologylipids (amino acids peptides and proteins)Lipid profileDyslipidemiaIron depletionlcsh:Q1-390

description

Here, we presented new original data on the effects of iron depletion on the circulating lipid profile in B6HCV mice, a murine model of HCV-related dyslipidemia. Male adult B6HCV mice were subjected to non-invasive iron depletion by low iron diet. Serum iron concentration was assessed for evaluating the effects of the dietary iron depletion. Concentrations of circulating triglycerides, total cholesterol, Low Density Lipoproteins (LDLs), High Density Lipoproteins (HDLs) were analyzed and reported by using stacked line charts. The present data indicated that low serum iron concentration is associated to i) lower serum triglycerides concentrations and ii) increased circulating LDLs. The presented original data have not been published elsewhere.

yearjournalcountryeditionlanguage
2017-06-01Data in Brief
10.1016/j.dib.2017.03.020http://www.sciencedirect.com/science/article/pii/S2352340917300963