6533b82efe1ef96bd1293af9

RESEARCH PRODUCT

Épidémiologie du cancer du pancréas

Anne-marie BouvierSylvain ManfrediCôme LepageAntoine Drouillard

subject

0301 basic medicineOncologyCancer Researchmedicine.medical_specialtybusiness.industryIncidence (epidemiology)Family aggregationHematologyGeneral Medicinemedicine.diseaseObesity03 medical and health sciences030104 developmental biology0302 clinical medicineOncology030220 oncology & carcinogenesisInternal medicinePancreatic cancerEpidemiologymedicineRadiology Nuclear Medicine and imagingPancreatic carcinogenesisAnnual variationbusinessNet Survival

description

Actually, pancreatic cancer is a major challenge in digestive oncology. Its prognosis remains very poor with a five-year net survival less than 10%. Although if pancreatic cancer incidence was low, data from French digestive cancer registries show a dramatic increase in recent years, more marked in women (annual variation of +3.6% between 1982 and 2012) than in men (+2.3%). The currently recognized risk factors like tobacco or obesity cannot explain this evolving epidemiology. Moreover, progress in understanding pancreatic carcinogenesis is still insufficient. Except for familial aggregation, systematic screening couldn't be proposed.

https://doi.org/10.1016/j.bulcan.2017.11.004