Intramolecular coupling of acetylenic groups of bis(alkynyl)phosphanes and silanes mediated by benzynezirconocene: a route to new mono- and tricyclic heterocycles

6533b82ffe1ef96bd1294615

RESEARCH PRODUCT

Intramolecular coupling of acetylenic groups of bis(alkynyl)phosphanes and silanes mediated by benzynezirconocene: a route to new mono- and tricyclic heterocycles

Alain Igau Philippe Meunier Nadine Pirio Peter Schuetz Bruno Donnadieu Jean-pierre Majoral Jean-claude Guillemin Laurence Dupuis Stephane Bredeau

subject

chemistry.chemical_classification Silanes Chemistry Organic Chemistry Heteroatom Thermal decomposition General Medicine Photochemistry Ring (chemistry)Biochemistry Medicinal chemistry Coupling (electronics)chemistry.chemical_compound C c coupling Main group element Intramolecular force Polymer chemistry Drug Discovery Tricyclic

description

Benzo-zirconacyclohexadiene-phospha or silacyclobutene fused ring systems are easily prepared via a benzynezirconocene intermediate by means of thermolysis of Cp 2 ZrPh 2 in the presence of bis(alkynyl)phosphanes or silanes. These polyunsaturated systems are the source of a variety of new mono- or tricyclic heterocycles incorporating either one or two heteroatoms.

year	journal	country	edition	language
2004-05-25	Tetrahedron

https://doi.org/10.1016/j.tet.2003.07.013

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