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RESEARCH PRODUCT
Supramolecular assembly of functional peptide-polymer conjugates.
Pol BeseniusRonja Ottersubject
Macromolecular SubstancesPolymersSupramolecular chemistryNanotechnologymacromolecular substances02 engineering and technology010402 general chemistry01 natural sciencesBiochemistrySupramolecular assemblyMoleculeHumansPhysical and Theoretical Chemistrychemistry.chemical_classificationMolecular StructureChemistryOrganic Chemistrytechnology industry and agriculturePolymer021001 nanoscience & nanotechnology0104 chemical sciencesSupramolecular polymers0210 nano-technologyPeptidesFunction (biology)MacromoleculeConjugatedescription
The following review gives an overview about synthetic peptide-polymer conjugates as macromolecular building blocks and their self-assembly into a variety of supramolecular architectures, from supramolecular polymer chains, to anisotropic 1D arrays, 2D layers, and more complex 3D networks. A selection of recent literature examples using linear, coiled-coil and cyclic peptide motifs is provided. The reversible nature of the unimer-to-supramolecular polymer transition provides unique opportunities to investigate mechanistic aspects of the supramolecular assembly, with respect to the thermodynamic or kinetic parameters and furthermore provides exciting opportunities for non-equilibrium assembly strategies. Using specific examples we also highlight some of the biological or mechanical function that arises from this versatile class of supramolecular biomaterials.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-06-27 | Organicbiomolecular chemistry |