6533b82ffe1ef96bd1295e3e

RESEARCH PRODUCT

Developmental dyslexia: re-evaluation of the corpus callosum in male adults.

Pascal BouchardJean-françois DémonetFabrice RobichonMichel Habib

subject

AdultMalemedicine.medical_specialtyAdult malePopulationAudiologyCorpus callosumCorpus CallosumDyslexiaReference ValuesmedicineHumanseducationeducation.field_of_studymedicine.diagnostic_testbusiness.industryMagnetic resonance imagingMagnetic Resonance ImagingSagittal planemedicine.anatomical_structureNeurologyIn uteroDevelopmental dyslexiaNeurology (clinical)businessNeurosciencePerinatal period

description

Using a new method based upon the measurement of four angles, we analyzed the corpus callosum of 23 adult male dyslexics and 25 age-matched controls on MRI sagittal scans. Two out of the four angles measured showed significant differences between the groups that are consistent with previous findings concerning the size of the corpus callosum in dyslexics. In particular, posterior regions are concerned, displaying a lowered corpus callosum in dyslexics. These findings are discussed in relation to cortical parietal asymmetries and possible hormonal events, referring to the testosterone hypothesis, that could occur in utero or in the perinatal period in the dyslexic population.

10.1159/000008182https://pubmed.ncbi.nlm.nih.gov/10828655