6533b82ffe1ef96bd1296221
RESEARCH PRODUCT
[Optimization of systemic treatments for chronic plaque psoriasis. Recommendations for switching and transitioning.]
Gisondi PAmerio PAmoroso GfAntonucci VaBardazzi FBuongiorno MrBruni PCampanati ACaproni MCarlesimo MCarrera CgCianchino GCimmino GAntonio CostanzoCozzani EDapavo PD'amico DDe Simone CDel Giglio MDi Nuzzo SGai FGalluccio AgGoffredo AGualdi GGuarneri CKokelj FLasagni CLoconsole FLongo VMalagoli PMiracapillo AMugheddu CParodi APellegrino MPeserico APiaserico SPistone GPotenza CPlumari AStingeni LStrippoli DTravaglino MGirolomoni Egsubject
switchingsystemic treatmentssystemic treatments; switching; transitioning; psoriasismoderate-severe chronic plaque psoriasispsoriasistransitioningSettore MED/35 - MALATTIE CUTANEE E VENEREEdescription
The aim of this study was to provide practical recommendations for optimizing the use of conventional and biological systemic treatments for moderate-severe chronic plaque psoriasis, particularly in case of transitioning and switching.A total number of 147 dermatologists from 33 different countries including Italy achieved consensus in providing practical recommendations for the use of conventional and biological treatments for moderate to severe psoriasis based on systematic literature review and/or expert opinion.In general, the continuous treatment regimen should be preferred in order to achieve a complete and long-term control of psoriasis. However, the treatment could be stopped or the dose reduced in case of complete disease clearance. A conventional drug could be associated to biological treatment in selected cases. Transitioning and/or switching could be considered in case of inefficacy or intolerance. A period of wash up is required if transitioning or switching is due to safety issues.This study provides practical suggestions for the optimal use of conventional and biological treatments for chronic plaque psoriasis.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-03-29 |