6533b82ffe1ef96bd12964a1

RESEARCH PRODUCT

Polymere 3-acryloyloxyalkyl- und 3-acryloyloxyaryl-4-thiazolidone als strahlenschutzsubstanzen

Rolando MontoyaIngo LüderwaldJorge SotoEckhard Schmidt

subject

chemistry.chemical_compoundMonomerWater solublechemistryPolymer chemistrymedicineCopolymerOrganic chemistryChlorideAcrylic acidmedicine.drug

description

The syntheses of 3-acryloyloxyalkyl- and 3-acryloyloxyaryl-2-phenyl-4-thiazolidones (3a–c) from the corresponding hydroxyl derivatives 2a–c and acrylic acid chloride are described. These monomers were homopolymerized and copolymerized with N-vinyl-2-pyrrolidone by radical initiation. The resulting water soluble copolymers were tested in animals for radioprotective activity and prolongation of efficiency.

https://doi.org/10.1002/macp.1977.021780501