6533b830fe1ef96bd1296fa7
RESEARCH PRODUCT
Der Einfluss von Acetylcholin auf den Calciumumsatz ruhender und kontrahierender Vorhofmuskulaturin vitro
H. LüllmannH Hoditzsubject
Pharmacologymedicine.medical_specialtyChemistrychemistry.chemical_elementCell BiologyCalciumCalcium uptakeIn vitroCell calciumCellular and Molecular NeuroscienceEndocrinologyInternal medicineCalcium contentcardiovascular systemmedicineMolecular MedicineAction potential durationMolecular BiologyAcetylcholinemedicine.drugdescription
Acetylcholine 5 × 10−8 g/ml reduces the Ca45 uptake of the beating left atria of guinea-pig; the tissue calcium is not altered. In resting atria, acetylcholine 5 × 10−7 g/ml has no influence upon the calcium content and Ca45 uptake. It is concluded that acetylcholine acts by shortening the action potential duration and thereby reduces the release of cellular calcium per excitation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1964-05-01 | Experientia |