6533b830fe1ef96bd1297bc4

RESEARCH PRODUCT

Associations of Time in Range and Other Continuous Glucose Monitoring–Derived Metrics With Well-Being and Patient-Reported Outcomes: Overview and Trends

Norbert HermannsAndreas SchmittBernhard KulzerDominic EhrmannLilli Priesterroth

subject

GerontologyContinuous glucose monitoringbusiness.industryEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismHypoglycemiamedicine.diseaseClinical Practice03 medical and health sciencesDistress0302 clinical medicineOpen researchWell-beingFrom Research to PracticeInternal MedicineClinical validitymedicine030212 general & internal medicinebusinessGlycemic

description

Time in glucose ranges is increasingly relevant for research and clinical practice. Whereas the clinical validity of these metrics has been demonstrated with regard to long-term complications, their associations with patient-reported outcomes such as well-being, diabetes distress, and fear of hypoglycemia remain an open research question. This article reviews existing evidence on links between times in glycemic ranges and patient-reported outcomes. It also describes a novel research approach of using ecological momentary assessment to analyze on a more granular level in real time possible associations of these parameters of glycemic control and patient-reported outcomes. Such an approach could further our understanding of how glucose and patient-reported outcomes may be interconnected.

https://doi.org/10.2337/ds20-0096