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RESEARCH PRODUCT

Transient Pulmonary Infiltrates during Treatment with Anti-Thymocyte Globulin

Natacha MaillardP. FoucherPhilippe CamusDenis CaillotChristine M. DurandCatherine Sgro

subject

Pulmonary and Respiratory Medicineendocrine systemPathologymedicine.medical_specialtyTime FactorsGlobulinAnemiamedicine.medical_treatmentmedicineAnimalsHumansAplastic anemiaLungAntilymphocyte SerumChemotherapybiologymedicine.diagnostic_testbusiness.industryRespiratory diseaseAnemia AplasticMiddle Agedmedicine.diseaseAnti-thymocyte globulinToxicitybiology.proteinFemaleRadiography ThoracicRabbitsTomography X-Ray ComputedChest radiographbusiness

description

We report the case of a 54-year-old woman with aplastic anemia, who developed transient pulmonary infiltrates following intravenous infusion of rabbit antithymocyte globulin (ATG) for 3 days. There was no other explanation than the infusion of ATG for the infiltrates. Rechallenge with ATG induced the recurrence of opacities on the chest radiograph. Although rarely involved with only 4 previous reports, ATG should be included in the list of drugs capable of inducing pulmonary infiltrates.

https://doi.org/10.1159/000029374