6533b831fe1ef96bd12990d6

RESEARCH PRODUCT

A topodiagnostic investigation on body lateropulsion in medullary infarcts.

Giorgio CruccuMarianne DieterichFrank ThömkeJürgen MarxPeter P. UrbanSabine FitzekGian Domenico IannettiH. C. HopfPeter Stoeter

subject

medicine.medical_specialtydifferentialHorner SyndromeMedullary cavitydiagnosisetiologyBrain mappingLesionDiagnosis DifferentialVestibular nucleiotorhinolaryngologic diseasesmedicineVertebrobasilar InsufficiencyHumansProspective StudiesLateral Medullary SyndromeBrain MappingProprioceptionLateral vestibulospinal tractbusiness.industryLimb ataxiaAnatomycomplications/physiopathologydiagnosis/etiology/physiopathologySurgerymedicine.anatomical_structureDiffusion Magnetic Resonance ImagingVestibular DiseasesSensation DisordersAtaxiaNeurology (clinical)Brainstemmedicine.symptombusinessDeglutition Disordersataxia; brain mapping; complications/physiopathology; deglutition disorders; diagnosis; diagnosis/etiology/physiopathology; differential; diffusion magnetic resonance imaging; etiology; horner syndrome; humans; lateral medullary syndrome; prospective studies; sensation disorders; vertebrobasilar insufficiency; vestibular diseases

description

Body lateropulsion may occur without signs of vestibular dysfunction and vestibular nucleus involvement. The authors examined 10 such patients with three-dimensional brainstem mapping. Body lateropulsion without limb ataxia reflected an impairment of vestibulospinal postural control caused by a lesion of the descending lateral vestibulospinal tract, whereas body lateropulsion with limb ataxia was probably the consequence of impaired or absent proprioceptive information caused by a lesion of the ascending dorsal spino-cerebellar tract.

10.1212/01.wnl.0000152040.27264.1ahttps://pubmed.ncbi.nlm.nih.gov/15728299