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RESEARCH PRODUCT

Serum metal levels in a population of Spanish pregnant women

Michael LeviLoreto Santa-marinaFerran BallesterSabrina LlopMikel AyerdiMario MurciaAmaia MolinuevoMiren Begoña ZuberoManuel LozanoAmaia Irizar

subject

IronPopulationtrace elementschemistry.chemical_elementPhysiologyCalciumOverweightSeleniumPregnancymedicineAnimalsHumansMagnesiumVitamin B12educationeducation.field_of_studyPregnancybusiness.industryIron levelsPublic Health Environmental and Occupational HealthVitaminsAnthropometrymedicine.diseaseTrace ElementsZincCross-Sectional StudieschemistryCalciumFemalePregnant Womenpregnancymedicine.symptombusinessserumCopperSelenium

description

Objective: To describe serum levels of calcium, copper, selenium, magnesium, iron and zinc and evaluate their relationship with maternal socio-demographic characteristics and dietary variables in women in the first trimester of pregnancy. Method: Cross-sectional study with 1279 participants from the INMA cohorts. Results: The concentrations of the elements analyzed were within the normal range. Associations with higher levels of these metals were found for calcium with white meat intake (p = 0.026), for cop-per with excess body weight (p 71 g/day) (p = 0.014) and having been born in Spain (p = 0.001). Further, lower iron levels were associated with being overweight (p = 0.021) or obese (p < 0.001) and vitamin B12 supplementation (p = 0.006). Conclusions: Our results suggest that trace elements in the analyzed cohorts are adequate for this stage of pregnancy. The variability in these elements is mainly linked to socio-demographic and anthropometric variables. This study is part of the INMA (Infancia y Medio Ambiente) project. It was supported by grants from Instituto de Salud Carlos III (FIS-FEDER: 06/0867, 09/00090, 13/1944, 16/1288, 19/1338; Miguel Servet-FEDER: CP15/0025; Miguel Servet-FSE: MS15/0025) , by the Council of Gipuzkoa (DFG15/009) and by the Health Department of the Basque Government.

https://doi.org/10.1016/j.gaceta.2021.07.006