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RESEARCH PRODUCT

Atrial fibrillation and cognitive disorders: An overview on possible correlation

Salvatore EvolaM. Chiara VizziniMonica LunettaDanilo PuccioGiuseppina NovoAlfredo R. GalassiValentina Baiamonte

subject

0301 basic medicineAgingmedicine.medical_specialtyPopulationCognitive declinemacromolecular substancesCognitive disorder03 medical and health sciences0302 clinical medicineInternal medicineAtrial FibrillationmedicineHumansDementiaCognitive Dysfunctioncardiovascular diseasesCognitive declineeducationPathologicalStrokeeducation.field_of_studybusiness.industryCardiac arrhythmiaAtrial fibrillationCognitionmedicine.diseaseStroke030104 developmental biologyCardiologyDementiabusiness030217 neurology & neurosurgeryDevelopmental Biology

description

Atrial Fibrillation is the most common cardiac arrhythmia affecting people of all ages, principally the elderly. Cognitive decline and dementia are also prevalent diseases in elderly. The scientific community always showed interest in the possible association between these two pathological entities, both implicating social and economic burden. This has been confirmed by several longitudinal population-based studies. Some studies also revealed that the association between atrial fibrillation and dementia may be not related to history of stroke. Therefore, other pathophysiological mechanisms are likely implicated, so far unclear or undefined. The aim of the present review is to analyse the possible mechanisms underlying the frequent association between atrial fibrillation and cognitive impairment.

https://doi.org/10.1016/j.mad.2020.111326