Role of cardiac computed tomography in the evaluation of coronary artery stenosis in patients with ascending aorta aneurysm detected at transthoracic echocardiography

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RESEARCH PRODUCT

Role of cardiac computed tomography in the evaluation of coronary artery stenosis in patients with ascending aorta aneurysm detected at transthoracic echocardiography

Daniele Ajello Massimo Midiri Massimo Galia Patrizia Toia Roberto Lagalla Emanuele Grassedonio Filippo Cademartiri Filippo Cademartiri Salvatore Novo Tommaso Vincenzo Bartolotta Giuseppina Novo Erica Maffei F Ludovico La Grutta

subject

Male medicine.medical_specialty Radiology Nuclear Medicine and Imaging Transthoracic echocardiography 030204 cardiovascular system & hematology Coronary Angiography Multimodal Imaging Sensitivity and Specificity 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences Aortic aneurysm 0302 clinical medicine Aneurysm medicine.artery Positive predicative value Internal medicine Ascending aorta medicine Cardiac CT Humans Aorta Aorta business.industry Coronary Stenosis Reproducibility of Results Middle Aged medicine.disease Aneurysm Aortic Aneurysm Stenosis medicine.anatomical_structure Echocardiography Cardiology Female Radiology Tomography X-Ray Computed business Settore MED/36 - Diagnostica Per Immagini E Radioterapia Artery

description

OBJECTIVE The aim of our study was to evaluate the diagnostic performance of cardiac computed tomography (CCT) in the evaluation of coronary artery stenosis in patients with ascending aorta aneurysm detected at transthoracic echocardiography. METHODS We conducted a retrospective analysis of patients with an aneurysm 45 mm or greater at transthoracic echocardiography who underwent CCT from 2012 to 2014 in our hospital. We calculated the sensitivity, specificity, and positive and negative predictive values of CCT for the assessment of coronary artery stenosis (<50% or ≥50% stenosis) in patients who underwent conventional coronary angiography. RESULTS We included 104 patients (73 men, aged 64 [SD, 10.8] years) in our study. Obstructive coronary artery disease was found in 22.1% of patients. Sensitivity, specificity, and positive and negative predictive values of CCT for detecting significant stenoses were 100%, 98%, and 82% and 100% on a segment-by-segment analysis and 100%, 83%, and 65% and 100% on a per-patient analysis, respectively. CONCLUSIONS Cardiac computed tomography provides a comprehensive evaluation of ascending aorta aneurysms and coronary artery tree.

year	journal	country	edition	language
2016-05-19

10.1097/rct.0000000000000380 http://hdl.handle.net/10447/203631