6533b833fe1ef96bd129b5d9

RESEARCH PRODUCT

ChemInform Abstract: Synthesis of 2-Isoxazolines: Enantioselective and Racemic Methods Based on Conjugate Additions of Oximes.

Antti PohjakallioUlla M. LaitinenPetri M. Pihko

subject

Addition reactionchemistry.chemical_compoundChemistryIntramolecular forceEnantioselective synthesisOrganic chemistryGeneral MedicineOximeConjugate

description

Acidic anilinium salts catalyze the direct formation of racemic 2-isoxazolines from enals and oximes by means of consecutive oxime conjugate-addition and intramolecular oxime-transfer reaction.

https://doi.org/10.1002/chin.201107160