Synthesis and antiviral activity of scopadulane-rearranged diterpenes.

6533b833fe1ef96bd129c1e2

RESEARCH PRODUCT

Synthesis and antiviral activity of scopadulane-rearranged diterpenes.

Lee Agudelo Miguel A. González Liliana Betancur-galvis

subject

Stereochemistry viruses Herpesvirus 2 Human Viral Plaque Assay Biology medicine.disease_cause Virus Replication Antiviral Agents Virus chemistry.chemical_compound Inhibitory Concentration 50 Pharmaceutical technology Virology Chlorocebus aethiops medicine Inhibitory concentration 50 Animals Vero Cells Pharmacology Molecular Structure Terpenoid Herpes simplex virus chemistry Biochemistry Diterpene Diterpenes Herpes virus simplex

description

A new bioactive diterpene skeleton resulting from a backbone rearrangement is described. Activity of the rearranged product and several derivatives against Herpes Virus Simplex type 2 is reported.

year	journal	country	edition	language
2009-11-13	Antiviral research

10.1016/j.antiviral.2010.01.001 https://pubmed.ncbi.nlm.nih.gov/20064563

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