6533b834fe1ef96bd129cb7a

RESEARCH PRODUCT

Acute acalculous cholecystitis during the course of primary Epstein–Barr virus infection: a new case and a review of the literature

Chiara IariaCiro FamulariMaria Grazia FracassiMaria Silvana LeonardiAntonio CascioGiovanni Di MaioLucia Arena

subject

AdultMicrobiology (medical)Epstein-Barr Virus Infectionsmedicine.medical_specialtyAdolescentmedicine.disease_causeGastroenterologyHerpesviridaeVirusacute acalculous; chotecystitis; gallbladder; Epstein-Barr virus; infectious mononucleosisEpstein–Barr virusInternal medicinemedicineEpstein-Barr viruschotecystitiHumansGammaherpesvirinaeInfectious mononucleosisEpstein–Barr virus infectionAcalculous Cholecystitischotecystitisbiologybusiness.industryGallbladderAcute acalculous cholecystitisGallbladderacute acalculousEpstein-Barr viruGeneral MedicineMiddle Agedbiology.organism_classificationmedicine.diseaseEpstein–Barr virusmedicine.anatomical_structureInfectious DiseasesImmunologyCholecystitisacute acalculouFemaleViral diseasebusiness

description

Summary Objective The aim of this study was to describe a case of acute acalculous cholecystitis occurring in the course of primary Epstein–Barr virus (EBV) infection. Methods The clinical features of the case were analyzed and compared to those of three other similar cases reported in the international literature. Results All cases occurred in European females with cholestatic hepatitis, presented with gallbladder wall thickening, and recovered uneventfully without the need for surgical intervention. Conclusions Acute acalculous cholecystitis may occur during the course of acute EBV infection, especially in patients with cholestatic hepatitis. Clinicians should be aware of the possible involvement of the gallbladder during EBV infection to avoid unnecessary invasive procedures or the overuse of antibiotics.

yearjournalcountryeditionlanguage
2008-07-01International Journal of Infectious Diseases
10.1016/j.ijid.2007.10.005http://dx.doi.org/10.1016/j.ijid.2007.10.005