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RESEARCH PRODUCT
Spatial analysis of the relationship between mortality from cardiovascular and cerebrovascular disease and drinking water hardness
Antionio Lopez-quilezJ.j. AbellánJ.j. AbellánHermelinda VanaclochaPilar SanmartínVirgilio Gómez-rubioRicardo OcañaSantiago Pérez-hoyosInmaculada MelchorFerran BallesterOscar ZurriagaMiguel A. Martinez-beneitoJuan FerrándizJose M. GilCarlos Abellansubject
GerontologyMaleMini-Monograph: Information SystemsHealth Toxicology and MutagenesisWater supply:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]Disease:Health Care::Environment and Public Health::Public Health::Sanitation::Sanitary Engineering::Water Supply [Medical Subject Headings]Magnesio:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]PreescolarMediana EdadReference ValuesExposición a Riesgos AmbientalesMedicineCluster AnalysisMagnesiumMasculinoChildEnfermedades Cardiovascularesgeographic information systems:Named Groups::Persons::Age Groups::Child::Child Preschool [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Weights and Measures::Reference Values [Medical Subject Headings]AdultoAguaEpidemiologic SurveillanceEnvironmental exposureMiddle AgedHumanos:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure [Medical Subject Headings]Abastecimiento de aguarelative risk:Information Science::Information Science::Information Storage and Retrieval::Databases as Topic::Databases Factual::Geographic Information Systems [Medical Subject Headings]Cardiovascular DiseasesNiñoChild Preschool:Diseases::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Cerebrovascular Disorders [Medical Subject Headings]Female:Named Groups::Persons::Age Groups::Infant [Medical Subject Headings]Risk assessmentAdulthierarchical spatial modelsAdolescentAncianoSistemas de Información Geográfica:Check Tags::Male [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Cluster Analysis [Medical Subject Headings]:Named Groups::Persons::Age Groups::Infant::Infant Newborn [Medical Subject Headings]Risk AssessmentCalcioWater Supply:Chemicals and Drugs::Inorganic Chemicals::Metals::Metals Alkaline Earth::Calcium [Medical Subject Headings]Environmental health:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]:Chemicals and Drugs::Inorganic Chemicals::Metals::Metals Light::Magnesium [Medical Subject Headings]Humans:Chemicals and Drugs::Inorganic Chemicals::Hydroxides::Water [Medical Subject Headings]:Named Groups::Persons::Age Groups::Adult::Aged [Medical Subject Headings]:Diseases::Cardiovascular Diseases [Medical Subject Headings]Socioeconomic status:Named Groups::Persons::Age Groups::Child [Medical Subject Headings]Agedbusiness.industry:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Assessment [Medical Subject Headings]Public Health Environmental and Occupational HealthInfant NewbornInfantWaterLactanteEnvironmental ExposureValores de ReferenciaAnálisis por ConglomeradosEstudios Epidemiológicosenvironmental epidemiologyCerebrovascular DisordersEpidemiologic StudiesTrastornos Cerebrovasculares:Check Tags::Female [Medical Subject Headings]Relative riskspatial smoothingCalciumbusinessMedición de Riesgo:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies [Medical Subject Headings]Environmental epidemiologydescription
Journal Article; Research Support, Non-U.S. Gov't; Reproduced with permission from Environmental Health Perspectives. Previously published scientific papers have reported a negative correlation between drinking water hardness and cardiovascular mortality. Some ecologic and case-control studies suggest the protective effect of calcium and magnesium concentration in drinking water. In this article we present an analysis of this protective relationship in 538 municipalities of Comunidad Valenciana (Spain) from 1991-1998. We used the Spanish version of the Rapid Inquiry Facility (RIF) developed under the European Environment and Health Information System (EUROHEIS) research project. The strategy of analysis used in our study conforms to the exploratory nature of the RIF that is used as a tool to obtain quick and flexible insight into epidemiologic surveillance problems. This article describes the use of the RIF to explore possible associations between disease indicators and environmental factors. We used exposure analysis to assess the effect of both protective factors--calcium and magnesium--on mortality from cerebrovascular (ICD-9 430-438) and ischemic heart (ICD-9 410-414) diseases. This study provides statistical evidence of the relationship between mortality from cardiovascular diseases and hardness of drinking water. This relationship is stronger in cerebrovascular disease than in ischemic heart disease, is more pronounced for women than for men, and is more apparent with magnesium than with calcium concentration levels. Nevertheless, the protective nature of these two factors is not clearly established. Our results suggest the possibility of protectiveness but cannot be claimed as conclusive. The weak effects of these covariates make it difficult to separate them from the influence of socioeconomic and environmental factors. We have also performed disease mapping of standardized mortality ratios to detect clusters of municipalities with high risk. Further standardization by levels of calcium and magnesium in drinking water shows changes in the maps when we remove the effect of these covariates. Yes
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2004-01-01 |