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RESEARCH PRODUCT
The 40-Year Mystery of Insect Odorant-Binding Proteins
Loïc BriandJean-françois FerveurKaren Rihanisubject
0301 basic medicineInsectaChemoreceptorOdorant bindinglcsh:QR1-502Gene ExpressionReviewInsectReceptors OdorantBiochemistryPheromoneslcsh:MicrobiologytasteSexual Behavior Animal0302 clinical medicinemedia_commonbiologyRihanichemosensory functionsArthropod mouthparts3. Good healthCell biologyDrosophila melanogasterodorant-protein-binding assayInsect ProteinsPheromoneDrosophila melanogasterolfactionmedia_common.quotation_subjectK.OlfactionFerveurEvolution Molecularnon-chemosensory functions03 medical and health sciencesAnimals[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyL. The 40-Year Mystery of Insect Odorant-Binding Proteins insectMolecular BiologyJ.-F.fungiBriandTransporterbiology.organism_classificationodorantprotein-binding assayHematopoiesis030104 developmental biologyinsect[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition030217 neurology & neurosurgerydescription
International audience; The survival of insects depends on their ability to detect molecules present in their environment. Odorant-binding proteins (OBPs) form a family of proteins involved in chemoreception. While OBPs were initially found in olfactory appendages, recently these proteins were discovered in other chemosensory and non-chemosensory organs. OBPs can bind, solubilize and transport hydrophobic stimuli to chemoreceptors across the aqueous sensilla lymph. In addition to this broadly accepted “transporter role”, OBPs can also buffer sudden changes in odorant levels and are involved in hygro-reception. The physiological roles of OBPs expressed in other body tissues, such as mouthparts, pheromone glands, reproductive organs, digestive tract and venom glands, remain to be investigated. This review provides an updated panorama on the varied structural aspects, binding properties, tissue expression and functional roles of insect OBPs.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-03-01 | Biomolecules |