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RESEARCH PRODUCT
Does Probiotic Yeast Act as Antigenotoxin?
Jekabs RaipulisInta KalninaReinis RutkisMalda Maija Tomasubject
Saccharomyces boulardiiSOS chromotestlcsh:Food processing and manufacturelcsh:TP368-456lcsh:Biotechnologylcsh:TP248.13-248.65antigenotoxicitygenotoxinsSaccharomyces boulardii; genotoxins; SOS chromotest; antigenotoxicitydescription
The effect of probiotic yeast Saccharomyces boulardii on genotoxicity induced by the well-known mutagen 4-nitroquinoline-N-oxide (4-NQO), as well as antibacterial (furazolidone) and antibiotic (nalidixic acid) drugs, has been studied using the short-term bacterial assay, SOS chromotest, with Escherichia coli PQ 37 as the test organism. It has been shown that S. boulardii possesses antigenotoxic activity, revealed by SOS chromotest, when coincubated with these genotoxins. A weaker antigenotoxic activity against the same compounds was observed with S. carlsbergensis, too.
year | journal | country | edition | language |
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2005-01-01 | Food Technology and Biotechnology |