6533b834fe1ef96bd129d462

RESEARCH PRODUCT

Synthesis of 1,3-Oxazolidines and 1,3-Dioxolanes by Reaction of (2R,3R)-3-Methylamino-3-phenyl-1,2-propanediol with Electrophiles.

José Sepúlveda-arquesElena Zaballos-garcíaChakib Hajji

subject

chemistry.chemical_compoundChemistryElectrophileOrganic chemistryGeneral MedicineDichloromethanePropanediol

description

Abstract The chemoselective reaction of (2R, 3R)-3-methylamino-3-phenyl-1,2-propanediol 1 with dimethoxypropane and dichloromethane under different conditions are reported as useful preparative procedures, for the synthesis 1,3-oxazolidines and 1,3-dioxolanes.

https://doi.org/10.1002/chin.200417113