6533b835fe1ef96bd129ea83

RESEARCH PRODUCT

Hyperpolarized 3helium gas as a novel contrast agent for functional MRI of ventilation.

Hans-ulrich Kauczor

subject

Lung Diseasesmedicine.medical_specialtyLungmedicine.diagnostic_testbusiness.industryContrast MediaMagnetic resonance imagingHeliumMagnetic Resonance Imagingmedicine.anatomical_structureIsotopesDynamic contrast-enhanced MRIAdministration InhalationmedicineBreathingRadiology Nuclear Medicine and imagingRadiologybusinessLung ventilationLung

description

The use of inhaled hyperpolarized 3He gas in MRI is a recent approach for ventilation imaging. It has recently received enormous interest since it is capable of producing new and regional information on normal and abnormal lung ventilation. Promising preclinical and preliminary clinical results are the driving force to start phase II trials with patients suffering from obstructive and restrictive lung diseases.

10.1016/s1076-6332(03)80277-5https://pubmed.ncbi.nlm.nih.gov/12188322