6533b835fe1ef96bd129ed5e

RESEARCH PRODUCT

First bodipy–DOTA derivatives as probes for bimodal imaging

Franck DenatClaire BernhardChristine GozeYoann Rousselin

subject

Boron CompoundsNuclear imagingStereochemistryMolecular ConformationGalliumIndiumCatalysisMolecular conformationHeterocyclic Compounds 1-Ringchemistry.chemical_compoundCoordination ComplexesMaterials ChemistryDOTAFluorescent DyesTomography Emission-Computed Single-PhotonMetals and AlloysGeneral ChemistryCombinatorial chemistryImaging agentSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryPositron-Emission TomographyIsothiocyanateCeramics and CompositesBODIPYCopper

description

The synthesis and the photophysical studies of the first bodipy-DOTA and its In(III), Ga(III) and Cu(II) complexes are reported. The introduction of an isothiocyanate handle generates a new bimodal imaging agent capable of both optical and nuclear imaging.

https://doi.org/10.1039/c0cc02749a