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RESEARCH PRODUCT
High-energy radiation processing, a smart approach to obtain PVP-graft-AA nanogels
Natascia GrimaldiGiuseppe SpadaroMaria Antonietta SabatinoSabina AlessiI. KaluskaDonatella BuloneMaria Luisa BondìG. PrzybytniakClelia Dispenzasubject
chemistry.chemical_classificationPoly(N-vinylpyrrolidone) Acrylic acid grafting Nanogels E-beam irradiationRadiationMaterials scienceAqueous solutionAbsorption spectroscopyInfrared spectroscopyPolymerchemistry.chemical_compoundMonomerchemistryChemical engineeringPolymer chemistrySettore CHIM/07 - Fondamenti Chimici Delle TecnologieSurface chargeSpectroscopyPoly(N-vinylpyrrolidone); acrylic acid grafting; nanogels; e-beam irradiation.Acrylic aciddescription
Abstract Poly(N-vinylpyrrolidone)-grafted-acrylic acid biocompatible nanogels (NGs) were prepared using an exiting industrial-type electron accelerator and setups, starting from semi-dilute aqueous solutions of a commercial PVP and the acrylic acid monomer. As a result, NGs with tunable size and structure can be obtained quantitatively. Sterility was also imparted at the integrated dose absorbed. The chemical structure of the NGs produced was confirmed through Fourier Transformer Infrared Spectroscopy (FT-IR). The molecular and physico-chemical properties of NGs, such as the hydrodynamic dimensions and surface charge densities, for various polymer and monomer concentrations in the irradiated solutions, are discussed here.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-01-01 | Radiation Physics and Chemistry |