6533b835fe1ef96bd129ffe6
RESEARCH PRODUCT
Progress in Arabidopsis genome sequencing and functional genomics
Micheline VandenbolM. BraekenP. MooijmanN. WeberM. LyneD. TaconB. ObermaierWim G. DirkseH. Van Den DaeleGuido VolckaertD FrishmannA. De KeyserP. KötterBénédicte PurnelleE. DefoorM. KayR. De ClercqSander PetersR. CookePetra BrandtE. PiravandiD. HaaseO. MassenetH. BlöckerManuel Pérez-alonsoI GyR. VillarroelLeo HeijnenWolfgang ZimmermannRosario LiguoriS. AubourgE. HolzerE. BentI. BastiaensT. GibbonsA. TorresM. GrimmM. ScharfeMartin D. WatsonD. BorkovaBerthold FartmannK. GranderathLeslie A. GrivellS. SchnablAnagnostis ArgiriouS. DoseA. DüsterhöftRita AertJ. GielenM. Van StaverenB. ReichertI. WeltjensMichael W. BevanElena CasacubertaS. BerneiserA. PettettAmparo MonfortC. BergerS Müller-auerBarbara HarrisL. ClarkK. MclayS. StockerThomas PohlM. KreisB. MccullaghR. MayesT. JesseC. BielkeM. RoseU. RamspergerK.-d. EntianWillem J. StiekemaMarleen VoetA.c. MaarseM. BraunMathias MüllerA. HerzlA Perez-perezH. HilbertF. VandenbusscheMichael A. QuailG. ClabauldS. Bray-allenSindy NeumannVladimir BenesJ. Van Der SchuerenPere PuigdomènechKai LemckeA. BrandtT. WeitzeneggerPatrik SchollerS. HempelS. SchwarzA. LecharnyF. QuigleyM. De HaanY. J. ChuangS. JohnsonC. GabelR. HillerC. BuysshaertT. SchmidtheiniM. FuchsJavier TerolMichel DelsenyW. SchmidtWilhelm AnsorgeL. BilhamA. CroninD. VitaleA. MündleinS. A. LanghamSteffen HeberMichael A. RiegerS. LamberthNicola LennardV De SimoneIan BancroftR. Klein LankhorstJoerg HoheiselD. PortatelleM. SchäferT. H. LöhnertS. HallR. WambuttP. VosC. SchüllerB. GrymonprezGeorge MurphyJane RogersM. FeldpauschJ. HaufM. WeichselgartnerP. ZaccariaR. MacheMarie-adèle RajandreamHans-werner MewesNancy TerrynS. RechmannG. BotheP. RidleyJ. DoggettKlaus F. X. MayerR. FelberMarc BoutryH. WedlerD. DaunerM. Van MontaguM. D. BarguesJohan Robbensubject
GeneticsGenome evolutionDNA PlantArabidopsis thalianaArabidopsisAgricultureBioengineeringGenomicsSequence Analysis DNAGeneral MedicineGenome projectBiologyGenome sequencingApplied Microbiology and BiotechnologyGenomeGenesCot analysisPlant Research InternationalGene densityGenome sizeGenome PlantBiotechnologyReference genomedescription
Arabidopsis thaliana has a relatively small genome of approximately 130 Mb containing about 10% repetitive DNA. Genome sequencing studies reveal a gene-rich genome, predicted to contain approximately 25 000 genes spaced on average every 4.5 kb. Between 10 to 20% of the predicted genes occur as clusters of related genes, indicating that local sequence duplication and subsequent divergence generates a significant proportion of gene families. In addition to gene families, repetitive sequences comprise individual and small clusters of two to three retroelements and other classes of smaller repeats. The clustering of highly repetitive elements is a striking feature of the A. thaliana genome emerging from sequence and other analyses.
year | journal | country | edition | language |
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2000-01-01 | Journal of Biotechnology |