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RESEARCH PRODUCT
Functional MRI of human primary somatosensory and motor cortex during median nerve stimulation.
Rolf-detlef TreedeJ. TinteraPeter StoeterJ. GawehnJörg Spiegelsubject
AdultSomatosensory systemBrain mappingPhysiology (medical)medicineHumansBrain Mappingmedicine.diagnostic_testMotor CortexMagnetic resonance imagingSomatosensory CortexMiddle AgedMagnetic Resonance ImagingSensory SystemsMedian nerveElectric StimulationMedian Nervemedicine.anatomical_structureNeurologySomatosensory evoked potentialNeurology (clinical)Primary motor cortexPsychologyFunctional magnetic resonance imagingNeuroscienceMotor cortexdescription
Abstract Objectives: Somatosensory evoked potential (SEP) studies suggested that some early cortical SEP components may be generated in the primary motor cortex (M1) rather than the primary somatosensory cortex (S1). Methods: We now used functional magnetic resonance imaging (fMRI) to study activation of S1 and M1 by electrical median nerve stimulation in healthy volunteers. Results: The hand areas of both S1 and M1 showed significant activation (correlation coefficients >0.45) in 7 of 9 subjects (activated volume S1>M1). For comparison, a sequential finger opposition task significantly activated S1 in 7 and M1 in all 9 subjects (activated volume M1>S1). Conclusions: These data show that the electrical stimuli used for SEP recording lead to a functional activation of S1 as well as M1.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1999-05-29 | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology |