6533b836fe1ef96bd12a0940

RESEARCH PRODUCT

Expanding spectrum of illness due to community-associated methicillin-resistant Staphylococcus aureus: a case report

Lorenzo DifrancescoRussell R. KempkerAlejandro Martin-gorgojoCarlos Franco-paredes

subject

Medicine(all)medicine.medical_specialtyAbdominal painPathologymedicine.drug_classbusiness.industrymedicine.medical_treatmentAntibioticsGeneral Medicinemedicine.disease_causemedicine.diseaseMethicillin-resistant Staphylococcus aureusNephrectomychemistry.chemical_compoundchemistryStaphylococcus aureusInternal medicineLinezolidCase reportmedicineVancomycinmedicine.symptomAbscessbusinessmedicine.drug

description

Introduction Xanthogranulomatous pyelonephritis is a rarely identified form of chronic pyelonephritis usually caused by gram-negative organisms. Herein, we report the first case caused by infection due to community-associated methicillin-resistant Staphylococcus aureus strain. Case presentation An HIV-infected female with a history of intravenous drug use presented with a three month history of abdominal pain, distension, and fever. Computerized tomography of the abdomen revealed a large multicystic right kidney mass. During surgical exploration an intrarenal abscess was identified. Cultures revealed the presence of community-associated methicillin-resistant Staphylococcus aureus. Histopathological examination demonstrated xanthogranulomatous disease. The patient was successfully treated with nephrectomy and a prolonged antibiotic combination regimen with vancomycin and linezolid. Conclusion Our case illustrates the escalating spectrum of illness caused by infection due to community-associated methicillin-resistant Staphylococcus aureus.

10.4076/1757-1626-2-7437http://europepmc.org/articles/PMC2769355