6533b836fe1ef96bd12a130c

RESEARCH PRODUCT

Glutamate Excitotoxicity in the Cerebellum Mediated by IL-1β

Raphael SchneiderAlma N. Mohebiany

subject

CerebellumAtaxiabusiness.industryGeneral NeuroscienceMultiple sclerosisEncephalomyelitisExcitotoxicityGlutamate receptorTreatment optionsmedicine.disease_causemedicine.diseasemedicine.anatomical_structureImmunologymedicinemedicine.symptomDemyelinating Disorderbusiness

description

Multiple sclerosis (MS) is the prototypic inflammatory demyelinating disorder of the CNS. Symptoms of cerebellar dysfunction, such as tremors and ataxia, are relatively common in MS, but available treatment options are generally of limited value. Although many clinical manifestations of MS are

https://doi.org/10.1523/jneurosci.3946-13.2013