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RESEARCH PRODUCT

Coffee drinking and risk of preterm birth

C. MaffiolettiLiliane ChatenoudLuca TozziVito ChianteraLuigi FedeleFrancesca ChiaffarinoElena RicciFabio ParazziniFabio Parazzini

subject

Adultmedicine.medical_specialtyPediatricsAdolescentEpidemiologyPregnancy Trimester ThirdMedicine (miscellaneous)CoffeeNormal for gestational agePregnancyCaffeineEpidemiologymedicineOdds RatioBirth WeightHumansRisk factorCoffee; Preterm birth; Risk factorsPregnancyNutrition and DieteticsObstetricsbusiness.industryRisk FactorCase-control studyInfant NewbornPregnancy OutcomeGestational agePreterm birthSmall for gestational ageOdds ratioMiddle Agedmedicine.diseaseRisk factorsCase-Control StudiesInfant Small for Gestational AgeSmall for gestational ageGestationPremature BirthFemaleCase-Control StudiebusinessInfant PrematureHumanFood Science

description

Objectives: We analysed the association between coffee drinking before and during the three trimesters of pregnancy and the risk of preterm birth of babies normal for gestational age (NGA) or small for gestational age (SGA). Methods: Case-control study conducted in University clinics of North Italy. Cases were 502 women who delivered at < weeks of gestation. The controls included 1966 women who gave birth at term (≥37 weeks of gestation) to healthy infants on randomly selected days at the hospitals where cases had been identified. Results: There was inverse association for coffee consumption in the third trimester of pregnancy in SGA cases compared to NGA (heterogeneity test between OR: χ12 P≤0.05). In comparison with not drinkers, all the ORs of overall intake of caffeine were closed near the unity for both SGA and NGA preterm birth. Conclusion: Compared with no consumption, a low consumption of coffee during pregnancy may not have significant effects on preterm birth. © 2006 Nature Publishing Group. All rights reserved.

10.1038/sj.ejcn.1602358http://hdl.handle.net/11695/5026